The Uprising of Women in Philanthropy (formerly When Women Lead) is a social justice playbook that documents the Global Women’s Funding Movement and is an urgent call for women’s collective leadership. The authors report the “Women Effect” that results from gender equality and women’s collective leadership, including improved public health and reproductive justice, expanded public education, more robust democracies, resilient economies, climate recovery, and enduring peace. The Global Women’s Funding Movement is guided by its Feminist Funding Principles, and through them, it has innovated the most influential philanthropic practices, including trust-based philanthropy.